Clinical manifestations / clinical symptoms that occur in
mesothelioma are dyspnea and chest pain nonpleuritic wall is the most common
symptom occurs in malignant mesothelioma.
Malignancy that involves the mesothelial cells of the
human body, including the pleura, peritoneum, pericardium, and testis, known as
malignant mesothelioma, either local or diffuse. Most, but not all, cases of
malignant mesothelioma (malignant mesothelioma) in the pleural (lung cancer)
usually associated with exposure to asbestos. Patients with malignant pleural
mesothelioma, 77% had been exposed to asbestos in the past. The diagnosis of
mesothelioma is difficult to enforce because of the results of the analysis of
effusion fluid from cancer usually does not terdiagnostik. Mesothelioma is more
common in men than women and it occurs most often in the age of fifth decade to
decade to 7. Most cases (about 90%) of malignant mesothelioma occurs in the
pleura.
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| Symptoms of Mesothelioma Cancer |
From the picture histologinya there are 3 types of
mesothelioma that sarcomata’s mesothelioma, epithelial, and mixed (mixed).
Pleural mesothelioma usually begins as plaques and nodules that combine to
produce sheet like neoplasm. Tumor growth usually begins at the bottom of the
chest. Tumors can invade the diaphragm and enveloped the surface of the lungs
and interlobar slits.
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| image peritoneum in abdominal cavity |
As the disease progresses, often extend into the lung
parenchyma, chest wall and mediastinum wall. Pleural mesothelioma can spread to
the esophagus, ribs, spine, brachial plexus, and the superior vena cava.
Asbestos, amphibole asbestos, asbestos-crocidolite, and
amosite asbestos in particular, is a major carcinogen involved in the
pathogenesis. Chrysotile asbestos exposure is associated with a lower incidence
of mesothelioma. Industrial area that often associating with the occurrence of
mesothelioma due to asbestos exposure, including the mining industry, ship
building which involves the use of asbestos, the manufacture of asbestos
cement, ceramics, paper mills, auto parts and railway repair factory.
Clinical manifestations / clinical symptoms that occur in
mesothelioma are:
- Dyspnea and chest pain nonpleuritic wall is the most common symptom occurs in malignant mesothelioma. (Approximately 60-90% of patients experienced symptoms of chest pain or dyspnea.)
- In patients with malignant mesothelioma, pleural effusion physical findings are usually known by percussion and auscultation.
- In rare cases, malignant mesothelioma manifests as cord compression, brachial plexopathy, Horner syndrome, or superior vena cava syndrome. Death is usually caused by an infection or respiratory failure of the development of mesothelioma.
- The main areas that often occurs in the pleura (87%), peritoneum (5.1%), and pericardium (0.4%).
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